Common variable immunodef w autoantibodies to B- or T-cells

This code signifies a primary immunodeficiency characterized by impaired B-cell differentiation and antibody production, specifically when autoantibodies targeting B-lymphocytes or T-lymphocytes are present. Patients typically present with recurrent infections, and the presence of these autoantibodies suggests an autoimmune component contributing to the immune dysregulation.

Apply this code when documentation explicitly states a diagnosis of common variable immunodeficiency (CVID) and laboratory findings confirm the presence of autoantibodies directed against B-cells or T-cells. This code is appropriate for patients with CVID who also exhibit an autoimmune manifestation related to these specific cellular targets.

• Ensure documentation clearly specifies "autoantibodies to B- or T-cells" in addition to the CVID diagnosis.
• Do not use this code if the CVID is not explicitly linked to these specific autoantibodies; consider other D83 subcategories.
• Code any associated autoimmune conditions or recurrent infections separately, following sequencing guidelines.