Com variab immunodef w predom immunoreg T-cell disorders

This code identifies a primary immunodeficiency characterized by impaired B-cell differentiation and antibody production, specifically when the predominant underlying defect involves immunoregulatory T-cells. Patients typically present with recurrent infections, particularly bacterial, and may also experience autoimmune manifestations or lymphoproliferation.

Assign this code for patients diagnosed with common variable immunodeficiency (CVID) where clinical and laboratory findings indicate a significant T-cell dysregulation as the primary immunoregulatory defect. Documentation should clearly specify CVID and mention T-cell involvement, such as abnormal T-cell subsets or function studies.

• Distinguish from other CVID subtypes (e.g., D83.0, D83.2) based on the specific predominant defect.
• Ensure documentation explicitly links the T-cell disorder to the CVID diagnosis.
• Code any associated infections or autoimmune conditions separately as secondary diagnoses.