Com variab immunodef w predom abnlt of B-cell nums & functn

This code represents a primary immunodeficiency characterized by impaired B-cell function, leading to significantly reduced serum immunoglobulin levels (IgG, IgA, and/or IgM) and recurrent infections. Patients typically present with an inability to produce adequate antibodies in response to antigens.

Apply this code for patients diagnosed with common variable immunodeficiency (CVID) where laboratory findings confirm a primary defect in B-cell numbers or their ability to produce functional antibodies. Documentation should specify hypogammaglobulinemia and recurrent infections consistent with CVID.

• Ensure documentation explicitly states "common variable immunodeficiency" and indicates B-cell involvement.
• Distinguish from other primary immunodeficiencies, especially those with T-cell defects, which have different codes.
• Code any associated infections or complications separately and sequence them after the CVID code.