Sicca syndrome

This code represents Sicca syndrome, also known as Sjögren's syndrome, a chronic autoimmune disorder characterized by dry eyes (xerophthalmia) and dry mouth (xerostomia) due to lymphocytic infiltration of the lacrimal and salivary glands. It can occur as a primary condition or secondary to other autoimmune diseases like rheumatoid arthritis or lupus.

Use this code when documentation clearly indicates a diagnosis of Sicca syndrome, whether primary or secondary. This diagnosis is typically supported by clinical findings of dry eyes and mouth, positive serological markers (e.g., anti-Ro/SSA, anti-La/SSB antibodies), and/or biopsy results showing glandular inflammation.

• Differentiate between primary Sicca syndrome and secondary manifestations. If secondary, code the underlying autoimmune disease first.
• Look for specific documentation of "Sicca syndrome" or "Sjögren's syndrome." Avoid using this code for isolated dry eye or dry mouth without a confirmed systemic diagnosis.
• Consider additional codes for specific manifestations or complications, such as keratoconjunctivitis sicca (370.33) or parotid gland enlargement (527.2).