Resistance to multiple antimycobacterial drugs

This code signifies that a patient's mycobacterial infection, such as tuberculosis, is resistant to several different types of antimycobacterial medications. This multi-drug resistance complicates treatment and often necessitates more aggressive or alternative therapeutic regimens.

Apply this code when laboratory testing confirms resistance to multiple antimycobacterial agents for a diagnosed mycobacterial infection. This is typically used in cases of multi-drug resistant tuberculosis (MDR-TB) or extensively drug-resistant tuberculosis (XDR-TB), where the specific drugs are not individually coded for resistance.

• Always sequence the underlying mycobacterial infection code first, followed by this resistance code.
• Ensure documentation clearly supports resistance to multiple antimycobacterial drugs, not just one.
• Do not use this code if resistance is only to a single antimycobacterial agent; use the appropriate specific resistance code instead.