Z16.19
ICD-10-CMThis code signifies that a bacterial infection is resistant to a beta-lactam antibiotic, other than those specifically classified elsewhere (e.g., penicillin, methicillin, cephalosporins). This resistance means the antibiotic will not be effective in treating the infection. It indicates a challenge in antimicrobial therapy due to the pathogen's insensitivity to a broad class of commonly used drugs.
Apply this code when laboratory testing (e.g., culture and sensitivity) confirms bacterial resistance to a beta-lactam antibiotic that is not covered by more specific resistance codes. This is often used in cases of multi-drug resistant organisms where resistance extends beyond the more common beta-lactam categories. It's crucial for documenting the need for alternative antibiotic regimens.
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