Resistance to single antimycobacterial drug

This diagnosis indicates that a patient's mycobacterial infection, such as tuberculosis, has shown resistance to a single antimicrobial agent used for treatment. This resistance means the specific drug is ineffective against the bacterial strain, necessitating a change in the therapeutic regimen.

Assign this code when laboratory testing (e.g., drug susceptibility testing) confirms resistance to only one antimycobacterial drug. This is applicable for patients undergoing treatment for mycobacterial diseases where a single agent has failed due to bacterial resistance. It is crucial for documenting the specific drug resistance profile to guide further treatment.

• Always sequence this code after the primary diagnosis for the mycobacterial infection (e.g., A15.- for tuberculosis).
• Ensure documentation clearly specifies resistance to only one antimycobacterial drug; do not use for multi-drug resistance.
• Verify that drug susceptibility test results support the single-drug resistance finding.