Resistance to antiparasitic drug(s)

This code signifies that a parasitic infection is not responding to standard antiparasitic medications. It indicates that the parasite has developed a mechanism to evade the drug's effects, leading to persistent or recurrent infection despite appropriate treatment. This resistance can be intrinsic to the parasite or acquired through genetic mutations.

Apply this code when a patient's parasitic infection has been documented as failing to respond to a prescribed antiparasitic drug regimen. This includes cases where initial treatment was ineffective, or where the infection recurred shortly after seemingly successful treatment with the same drug. It is used to specify the presence of drug resistance, not merely treatment failure due to non-compliance or incorrect dosage.

• Always sequence this code after the code for the specific parasitic infection.
• Ensure documentation clearly states the antiparasitic drug(s) used and the evidence of resistance (e.g., persistent symptoms, positive follow-up labs).
• Do not use this code for general treatment failure without explicit documentation of drug resistance.