Organ-limited amyloidosis

This code represents amyloidosis that is confined to a single organ or a specific anatomical site, rather than being a systemic or widespread disease. It involves the abnormal deposition of amyloid proteins within a localized area, impairing the function of that particular organ.

Use this code when documentation clearly specifies amyloid deposition affecting only one organ, such as localized amyloidosis of the bladder, larynx, or skin. This diagnosis is typically confirmed by biopsy showing amyloid deposits restricted to the identified organ.

• Differentiate carefully from systemic amyloidosis (E85.0-E85.3, E85.8-E85.9), which affects multiple organs.
• Ensure documentation explicitly states "organ-limited" or specifies a single affected organ without evidence of systemic involvement.
• Code the specific manifestation or affected organ as an additional diagnosis if clinically relevant and documented.