Acute myelomonocytic leukemia, not having achieved remission

This code represents a specific type of acute myeloid leukemia (AML) characterized by the proliferation of both myeloid and monocytic blast cells. It indicates that the patient's disease is currently active and has not responded to treatment sufficiently to be considered in remission. This aggressive hematologic malignancy requires immediate and intensive therapy.

Apply this code when documentation confirms a diagnosis of acute myelomonocytic leukemia (AMML) and explicitly states that the patient has not achieved remission. This is typically used for newly diagnosed cases, relapsed disease, or when treatment has failed to induce remission. Supporting documentation includes pathology reports, bone marrow biopsies, and physician notes detailing the disease status.

• Differentiate from other AML subtypes; ensure documentation specifically identifies the myelomonocytic lineage.
• Do not use if the patient is in remission, even if they have a history of AMML; instead, use codes for personal history or relapse.
• Consider sequencing with codes for complications of the disease or treatment, such as anemia or thrombocytopenia, as appropriate.