Chronic myeloid leukemia, BCR/ABL-positive, in relapse

This code represents chronic myeloid leukemia (CML) that is characterized by the presence of the BCR/ABL fusion gene, indicating a specific genetic abnormality. The "in relapse" designation signifies that the disease, after a period of remission, has returned or progressed.

Use this code when documentation clearly states a diagnosis of BCR/ABL-positive CML that has recurred or shown signs of progression after previous treatment. This typically applies to patients who have achieved a molecular or cytogenetic remission and are now experiencing a return of leukemic cells.

• Ensure documentation explicitly states "BCR/ABL-positive" and "in relapse" for accurate code assignment.
• Distinguish from CML in remission (C92.11) or CML, unspecified (C92.10).
• Sequence as the primary diagnosis when it is the reason for the encounter; otherwise, it may be a secondary diagnosis.