Acute promyelocytic leukemia, in relapse

This code signifies a specific type of acute myeloid leukemia (AML) characterized by a proliferation of abnormal promyelocytes, which has recurred after a period of remission. It indicates that the disease, previously treated, has returned and is currently active.

Apply this code when documentation explicitly states a diagnosis of acute promyelocytic leukemia (APL) and specifies that the condition is in relapse. This is typically used for patients undergoing treatment for recurrent APL.

• Differentiate from APL in remission or APL not otherwise specified.
• Ensure documentation clearly states "relapse" or "recurrent" for APL.
• Consider sequencing with codes for current treatment modalities (e.g., chemotherapy, stem cell transplant).