Acute promyelocytic leukemia, not having achieved remission

This code signifies a specific subtype of acute myeloid leukemia (AML) characterized by a chromosomal translocation involving the retinoic acid receptor alpha (RARA) gene. It indicates that the patient is currently experiencing the active disease and has not yet achieved a state of remission following treatment.

Use this code for patients diagnosed with acute promyelocytic leukemia (APL) who are undergoing initial treatment or have relapsed and are not in remission. Documentation should clearly state the diagnosis of APL and explicitly indicate the absence of remission, often through bone marrow biopsy results or clinical assessment.

• Do not use this code if the patient is in remission; instead, refer to codes for APL in remission.
• Ensure documentation specifies "acute promyelocytic" as opposed to other types of acute myeloid leukemia.
• Consider sequencing this code as the primary diagnosis when it is the reason for the encounter.