Myeloid sarcoma, not having achieved remission

This code signifies myeloid sarcoma, also known as granulocytic sarcoma or chloroma, which is an extramedullary tumor composed of immature myeloid cells. It represents a localized proliferation of leukemic blasts occurring outside the bone marrow, skin, or lymph nodes, and specifically indicates that the disease has not yet achieved remission.

Apply this code when documentation confirms a diagnosis of myeloid sarcoma and explicitly states that the patient is not in remission. This typically occurs during initial diagnosis, active treatment phases, or when the disease is refractory to treatment. Supporting documentation includes pathology reports confirming myeloid sarcoma and physician notes indicating ongoing disease activity.

• Differentiate from other extramedullary manifestations of leukemia; this code is specific to myeloid sarcoma.
• Ensure documentation clearly states "not in remission" to avoid miscoding with codes for myeloid sarcoma in remission.
• Sequence this code as the primary diagnosis when the myeloid sarcoma is the reason for the encounter, followed by codes for any associated acute myeloid leukemia (AML) if present.