Lymphocyte depleted Hodgkin lymphoma, lymph nodes mult site

This code signifies a rare and aggressive subtype of Hodgkin lymphoma characterized by a scarcity of lymphocytes and an abundance of Reed-Sternberg cells. The disease has spread to involve lymph nodes in multiple, non-contiguous anatomical regions. This particular form often presents in older adults and may have a less favorable prognosis than other Hodgkin lymphoma subtypes.

Assign this code when documentation explicitly states a diagnosis of lymphocyte-depleted Hodgkin lymphoma affecting lymph nodes in more than one body region. Supporting documentation should include pathology reports confirming the specific subtype and imaging or clinical notes detailing the multifocal lymph node involvement. This code is typically used for initial diagnosis or subsequent treatment episodes where the extent of disease remains relevant.

• Ensure pathology reports definitively identify the "lymphocyte depleted" subtype, as other Hodgkin lymphoma subtypes have distinct codes.
• Verify that documentation clearly indicates involvement of lymph nodes in "multiple sites" to differentiate from single-site involvement.
• Sequence this code as the primary diagnosis when it is the reason for the encounter, followed by any associated complications or treatment-related conditions.