Nodular lymphocyte predominant Hodgkin lymphoma, spleen

This diagnosis code signifies a specific subtype of Hodgkin lymphoma, characterized by a nodular growth pattern and a predominance of lymphocytes, with the primary site of involvement being the spleen. It represents a less aggressive form of Hodgkin lymphoma compared to classical types.

Apply this code when documentation clearly states a diagnosis of nodular lymphocyte predominant Hodgkin lymphoma (NLPHL) with confirmed splenic involvement. This typically follows a biopsy and histopathological examination confirming the specific NLPHL subtype and imaging or surgical findings indicating splenic disease.

• Ensure the pathology report specifically identifies "nodular lymphocyte predominant" Hodgkin lymphoma, not just "Hodgkin lymphoma."
• Verify that the medical record explicitly documents splenic involvement as the primary or a significant site of disease.
• Do not confuse with classical Hodgkin lymphoma subtypes, which are coded differently.