Nodular lymphocyte predominant Hodgkin lymphoma, unsp site

This code identifies a specific, less aggressive subtype of Hodgkin lymphoma characterized by the presence of "popcorn" cells (lymphocytic and histiocytic cells) and a nodular growth pattern. It represents a malignant neoplasm originating from B-lymphocytes within lymph nodes, primarily affecting the immune system.

Assign this code when the medical record clearly documents a diagnosis of nodular lymphocyte predominant Hodgkin lymphoma (NLPHL) without specifying the primary anatomical site of involvement. This is appropriate when the diagnostic workup confirms NLPHL but the exact location (e.g., lymph node group, extranodal) is not yet determined or documented.

• Do not use this code if a specific anatomical site of NLPHL is documented; instead, use a more specific C81.0- subcategory.
• Ensure the pathology report explicitly states "nodular lymphocyte predominant Hodgkin lymphoma" to support this diagnosis.
• Always sequence this code as the primary diagnosis when it is the reason for the encounter or treatment.