Mixed cellular Hodgkin lymph, extrnod and solid organ sites

This diagnosis code signifies a specific type of Hodgkin lymphoma characterized by a heterogeneous cellular infiltrate, including Reed-Sternberg cells, lymphocytes, eosinophils, and plasma cells, that has originated or spread to sites outside of the lymphatic system, such as the bone marrow, liver, or lungs. It represents a systemic malignancy affecting non-lymphoid tissues.

This code is appropriate for patients diagnosed with mixed cellularity Hodgkin lymphoma where the disease is confirmed to be present in extranodal locations or solid organs. Documentation should clearly state the specific extranodal site(s) involved, such as "mixed cellularity Hodgkin lymphoma with bone marrow involvement" or "mixed cellularity Hodgkin lymphoma with pulmonary metastases."

• Ensure the pathology report explicitly states "mixed cellularity" and identifies extranodal or solid organ involvement.
• Do not use this code for nodal involvement only; specific codes exist for Hodgkin lymphoma affecting lymph nodes.
• Always sequence this code as the primary diagnosis when it is the reason for the encounter or hospitalization.