Nodular sclerosis Hodgkin lymphoma, spleen

This code signifies a diagnosis of Hodgkin lymphoma, specifically the nodular sclerosis subtype, with confirmed involvement of the spleen. Nodular sclerosis is the most common histological subtype of Hodgkin lymphoma, characterized by collagen bands and lacunar cells.

This code is appropriate when diagnostic workup, such as biopsy and imaging, confirms nodular sclerosis Hodgkin lymphoma with documented splenic involvement. Documentation should clearly state the subtype and the affected anatomical site.

• Ensure the pathology report explicitly states "nodular sclerosis" and not another Hodgkin lymphoma subtype.
• Confirm splenic involvement is documented, not just generalized lymphadenopathy.
• Always sequence this code as the primary diagnosis when it is the reason for the encounter.