Nodular lymphocyte predom Hodgkin lymphoma, nodes mult site

This code identifies a specific subtype of Hodgkin lymphoma, Nodular Lymphocyte Predominant Hodgkin Lymphoma (NLPHL), when it affects lymph nodes in more than one anatomical region. NLPHL is characterized by the presence of "popcorn cells" (LP cells) and a nodular growth pattern, distinguishing it from classical Hodgkin lymphoma.

Apply this code when documentation confirms a diagnosis of Nodular Lymphocyte Predominant Hodgkin Lymphoma involving multiple lymph node sites. This typically requires pathology reports confirming the NLPHL subtype and imaging or clinical notes indicating involvement of lymph nodes in disparate regions (e.g., cervical and inguinal).

• Ensure the pathology report specifically states "Nodular Lymphocyte Predominant Hodgkin Lymphoma" and not a classical Hodgkin lymphoma subtype.
• Verify that documentation clearly indicates involvement of lymph nodes in multiple, distinct anatomical regions.
• Do not use this code for single-site involvement; specific codes exist for single anatomical regions.