Hereditary nephrop, NEC with APOL1-mediated kidney disease

This code identifies hereditary kidney disease that is not specified elsewhere, specifically when it is caused by genetic variations in the Apolipoprotein L1 (APOL1) gene. This condition often leads to progressive kidney damage and can result in end-stage renal disease.

Use this code for patients diagnosed with a hereditary nephropathy where genetic testing confirms the presence of APOL1-mediated kidney disease. Documentation should clearly state the diagnosis of hereditary nephropathy and explicitly link it to APOL1 gene variants.

• Ensure documentation specifies "APOL1-mediated" to differentiate from other hereditary nephropathies.
• This code should be sequenced as the primary diagnosis when the APOL1-mediated kidney disease is the reason for the encounter.
• Do not use this code if the hereditary nephropathy is classified elsewhere (e.g., Alport syndrome, Fabry disease).