Tropical sprue

This code identifies tropical sprue, a chronic malabsorption syndrome characterized by abnormalities of the small intestinal mucosa, leading to nutrient deficiencies. It is acquired and typically affects individuals residing in or visiting tropical and subtropical regions.

Assign this code for patients diagnosed with tropical sprue, often presenting with chronic diarrhea, weight loss, and evidence of malabsorption such as megaloblastic anemia. Documentation should clearly indicate a diagnosis of tropical sprue, often supported by biopsy findings consistent with villous atrophy and clinical response to broad-spectrum antibiotics and folic acid.

• Differentiate from celiac disease (K90.0) and other malabsorption syndromes; tropical sprue is not gluten-induced.
• Ensure documentation specifies "tropical sprue" to avoid confusion with other forms of sprue or enteropathy.
• Code any associated nutritional deficiencies (e.g., E53.8 for other specified B vitamin deficiency) as secondary diagnoses.