Tropical sprue

This code represents tropical sprue, a chronic malabsorption syndrome primarily affecting individuals in tropical and subtropical regions. It is characterized by damage to the small intestinal lining, leading to impaired absorption of nutrients, particularly folate and vitamin B12.

Use this code for patients diagnosed with tropical sprue based on clinical presentation, histological findings from small bowel biopsy (e.g., villous atrophy, crypt hyperplasia), and exclusion of other causes of malabsorption. Documentation should clearly indicate the diagnosis of tropical sprue, often supported by a history of travel to endemic areas.

• Differentiate from celiac disease; tropical sprue does not respond to a gluten-free diet.
• Consider co-occurring nutritional deficiencies (e.g., folate, B12, iron) and code them separately if documented.
• Ensure documentation specifies "tropical" sprue to avoid confusion with other forms of malabsorption.