Non-celiac gluten sensitivity

This code represents a condition where individuals experience gastrointestinal and/or extra-intestinal symptoms after consuming gluten, but without the autoimmune damage characteristic of celiac disease or a wheat allergy. It is a diagnosis of exclusion, typically made after celiac disease and wheat allergy have been ruled out.

Use this code for patients presenting with symptoms such as abdominal pain, bloating, diarrhea, fatigue, or headache, where diagnostic testing for celiac disease (e.g., negative tissue transglutaminase IgA, negative duodenal biopsy) and wheat allergy (e.g., negative IgE specific to wheat) has been negative. Documentation should clearly indicate a symptomatic response to gluten ingestion and symptom resolution on a gluten-free diet.

• Ensure celiac disease (K90.0x) and wheat allergy (T78.0x) have been explicitly ruled out in the medical record.
• Do not use this code if the patient has a confirmed diagnosis of celiac disease or wheat allergy.
• Consider sequencing this code as the primary diagnosis if it is the main reason for the encounter, followed by codes for associated symptoms if applicable.