Genetic anomalies of leukocytes

This code signifies inherited or congenital abnormalities affecting the structure, function, or number of white blood cells (leukocytes). These anomalies are present from birth and can impact various leukocyte types, potentially leading to immune deficiencies, increased susceptibility to infections, or other hematologic disorders.

Use this code when documentation indicates a genetically determined defect in leukocyte development or morphology, such as Pelger-Huët anomaly, Chédiak-Higashi syndrome, or other inherited white blood cell disorders. Supporting documentation would include genetic testing results, bone marrow biopsy findings, or a confirmed diagnosis from a hematologist.

• Do not use for acquired leukocyte disorders; these typically fall under other categories like aplastic anemia or myelodysplastic syndromes.
• Always sequence this code as a primary diagnosis if it is the reason for the encounter, or as a secondary diagnosis if it contributes to the patient's overall condition.
• Ensure the medical record clearly distinguishes between congenital/inherited conditions and acquired conditions affecting leukocytes.