High grade intrepith lesion cyto smr anus (HGSIL)

This code signifies the presence of high-grade squamous intraepithelial lesions (HGSIL) detected in an anal cytologic smear. HGSIL represents significant precancerous changes in the anal canal's squamous cells, indicating a high risk of progression to invasive anal cancer.

Use this code when pathology reports confirm HGSIL on an anal Pap test or anal cytology. This typically occurs during screening for anal dysplasia, especially in high-risk populations such as HIV-positive individuals or those with a history of receptive anal intercourse.

• Ensure the documentation explicitly states "high-grade" and "squamous intraepithelial lesion" from an "anal" cytologic smear.
• Do not confuse with low-grade squamous intraepithelial lesions (LSIL) or atypical squamous cells of undetermined significance (ASCUS).
• This code is for the cytologic finding; subsequent biopsy results confirming dysplasia would be coded separately.