Neurodev disord, rel to patho var in other synapse rel gene

This code describes a neurodevelopmental disorder caused by a genetic mutation in a gene involved in synapse function, excluding those specifically categorized elsewhere. These disorders typically present with a range of developmental delays, intellectual disability, and often behavioral or neurological abnormalities, stemming from impaired communication between neurons.

Use this code when documentation confirms a neurodevelopmental disorder and genetic testing identifies a pathogenic variant in a synapse-related gene not otherwise classified. This diagnosis is supported by genetic reports detailing the specific gene mutation and its classification as pathogenic, alongside clinical assessments outlining the neurodevelopmental phenotype.

• Ensure the genetic report explicitly states a "pathogenic variant" or "likely pathogenic variant" in a synapse-related gene.
• Do not use this code if the specific synapse-related gene has its own dedicated ICD-10-CM code.
• Sequence this code as a primary diagnosis when it is the main reason for the encounter, or as a secondary diagnosis when it contributes to the patient's overall condition.