Azoospermia due to systemic disease

This code signifies the complete absence of sperm in the ejaculate, specifically when the underlying cause is a systemic medical condition affecting the body as a whole. It indicates a form of male infertility directly attributable to a broader health issue rather than a localized testicular or reproductive tract problem.

Apply this code when documentation clearly states azoospermia and explicitly links it to a systemic disease, such as certain endocrine disorders, genetic conditions, or chronic illnesses. Supporting documentation should include diagnostic test results confirming azoospermia and a physician's assessment identifying the systemic etiology.

• Ensure the medical record explicitly states "due to systemic disease" to differentiate from other forms of azoospermia.
• Always code the underlying systemic disease first, followed by this code as a secondary diagnosis.
• Do not use this code for obstructive or non-obstructive azoospermia without a documented systemic cause.