Hematpoetc stem cell txpltation-assoc throm microangiopathy

This code represents a severe and often life-threatening complication following hematopoietic stem cell transplantation (HSCT), characterized by microvascular injury, endothelial damage, and microthrombi formation. It leads to organ dysfunction, particularly affecting the kidneys, brain, and lungs. This condition is distinct from other post-transplant complications like graft-versus-host disease.

Use this code for patients who develop thrombotic microangiopathy specifically as a consequence of receiving a hematopoietic stem cell transplant. Documentation should clearly state the diagnosis of HSCT-TMA, often supported by clinical findings such as microangiopathic hemolytic anemia, thrombocytopenia, and evidence of organ damage (e.g., renal insufficiency, neurological symptoms) occurring post-transplant.

• Ensure documentation explicitly links the thrombotic microangiopathy to the prior hematopoietic stem cell transplant.
• Do not confuse with other forms of thrombotic microangiopathy (e.g., atypical HUS, TTP) unless they are also present and separately documented.
• Sequence this code as a primary diagnosis when it is the reason for the encounter, or as a secondary diagnosis when it is a co-morbidity impacting care.