Oth psychoactv substance depend w persist amnestic disorder

This code signifies a patient's physiological and psychological dependence on a psychoactive substance other than alcohol, opioids, cannabis, sedatives, hypnotics, anxiolytics, stimulants, hallucinogens, or inhalants. This dependence is accompanied by a persistent, substance-induced amnestic disorder, characterized by significant memory impairment that developed during or soon after substance intoxication or withdrawal. The memory deficit is not attributable to another mental or medical condition.

Apply this code when documentation clearly indicates a diagnosis of dependence on a specified "other" psychoactive substance (e.g., phencyclidine, volatile solvents, or multiple substances not otherwise specified) alongside a persistent amnestic disorder directly attributed to that substance use. Supporting documentation should detail the substance(s) involved, evidence of dependence, and the presence of ongoing, significant memory impairment.

• Ensure the specific psychoactive substance is documented as "other" and not one with a more specific ICD-10-CM category.
• Verify that the amnestic disorder is explicitly stated as "persisting" and "substance-induced," not a pre-existing or unrelated memory issue.
• Sequence this code as the primary diagnosis when the substance dependence and associated amnestic disorder are the main reasons for the encounter.