Opioid dependence with opioid-induced mood disorder

This diagnosis code signifies a patient's physiological and psychological dependence on opioids, where the chronic use of these substances has directly resulted in a mood disturbance. This mood disorder can manifest as depression, anxiety, or other affective symptoms that are clearly attributable to the opioid use.

Apply this code when documentation explicitly links a patient's mood disorder to their opioid dependence. This typically requires a physician's assessment confirming both the dependence and the causal relationship of the opioids to the mood disturbance, rather than a pre-existing or co-occurring independent mood disorder.

• Ensure the medical record clearly states the mood disorder is "opioid-induced" or "due to opioid use."
• Do not use this code if the mood disorder predates or is independent of the opioid dependence; consider codes for primary mood disorders and opioid dependence without mood complications.
• Sequence this code as the primary diagnosis if the opioid dependence with mood disorder is the reason for the encounter, followed by any specific mood disorder codes if further specificity is needed (e.g., F32.9 for major depressive disorder, unspecified, if documented as opioid-induced).