Opioid dependence with intoxication delirium

This code signifies a patient's physiological and psychological reliance on opioids, accompanied by acute brain dysfunction (delirium) directly caused by opioid intoxication. The delirium manifests as a disturbance in attention, awareness, and cognition, developing over a short period. This condition represents a severe manifestation of opioid use disorder.

Apply this code when documentation clearly indicates both opioid dependence and a concurrent state of delirium directly attributable to acute opioid intoxication. This typically occurs in acute care settings or emergency departments where patients present with altered mental status alongside signs of opioid use disorder. Supporting documentation includes physician notes detailing diagnostic criteria for both opioid dependence and intoxication delirium, often with toxicology screens confirming opioid presence.

• Ensure documentation explicitly links the delirium to opioid intoxication, not other causes.
• Do not use this code if the delirium is due to opioid withdrawal; a different code would apply.
• Always sequence this code as the primary diagnosis if it is the reason for the encounter.