Glucocorticoid-remediable aldosteronism

This code identifies a specific genetic form of primary aldosteronism, an endocrine disorder characterized by excessive aldosterone production by the adrenal glands. This overproduction leads to hypertension and hypokalemia, and importantly, the condition is responsive to glucocorticoid therapy.

Apply this code when documentation confirms a diagnosis of glucocorticoid-remediable aldosteronism, often established through genetic testing for a chimeric gene (CYP11B1/CYP11B2) or a positive dexamethasone suppression test. This code is appropriate for patients presenting with primary aldosteronism who show a favorable blood pressure response to low-dose glucocorticoids.

• Ensure documentation explicitly states "glucocorticoid-remediable" or "GRA" to support this specific diagnosis.
• Differentiate from other forms of primary aldosteronism, such as aldosterone-producing adenoma (Conn's syndrome) or bilateral adrenal hyperplasia.
• Code any associated manifestations like hypertension or hypokalemia as secondary diagnoses.