Von Willebrand disease, type 2B

📋Clinical Description

This code represents a specific inherited bleeding disorder characterized by a qualitative defect in von Willebrand factor (VWF) due to increased affinity for platelets. Type 2B VWD leads to spontaneous binding of VWF to platelets, causing their premature clearance and resulting in thrombocytopenia and bleeding symptoms.

🎯When to Use

Use this code for patients diagnosed with Von Willebrand disease, specifically identified as type 2B, based on laboratory testing. Documentation should clearly indicate the specific subtype of VWD, often confirmed by VWF multimer analysis, ristocetin-induced platelet aggregation (RIPA) studies, and genetic testing.

💡Coding Tips

Ensure documentation specifies "type 2B" VWD; do not use for other VWD types.
Distinguish from other qualitative VWD types (2A, 2M, 2N) which have different code assignments.
Code any associated bleeding manifestations or complications separately, if applicable.

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Clinical Notes

Inclusion Terms

Qualitative defects of von Willebrand factor with high-molecular-weight von Willebrand factor loss
Qualitative defects of von Willebrand factor with hyper-adhesive forms
Qualitative defects of von Willebrand factor with increased affinity for platelet glycoprotein lb

Code Hierarchy

▲D68.02Von Willebrand disease, type 2

D68.021(current)

Same Category

D68Other coagulation defects D68.0Von Willebrand disease D68.00Von Willebrand disease, unspecified D68.01Von Willebrand disease, type 1 D68.02Von Willebrand disease, type 2 D68.020Von Willebrand disease, type 2A D68.022