Acute erythroid leukemia, in relapse

This code signifies a diagnosis of acute erythroid leukemia (AEL) that has recurred after a period of remission. AEL is a rare and aggressive subtype of acute myeloid leukemia characterized by the proliferation of immature red blood cell precursors. "In relapse" indicates the disease has returned following previous treatment.

Apply this code when documentation explicitly states a diagnosis of acute erythroid leukemia and specifies that the disease is currently in relapse. This typically follows a period of complete or partial remission, confirmed by bone marrow biopsy and peripheral blood counts showing re-emergence of leukemic blasts.

• Always confirm "in relapse" status; do not assume based on treatment alone.
• Distinguish from "in remission" (C94.01) or "not achieved remission" (C94.00).
• Code any associated complications or manifestations of the relapse separately.