Non-Hodgkin lymphoma, unspecified, spleen

This code signifies a malignant proliferation of lymphocytes within the spleen, where the specific type of non-Hodgkin lymphoma (NHL) has not been definitively identified through pathology. It indicates a primary or secondary involvement of the spleen by an unspecified NHL.

Use this code when documentation confirms non-Hodgkin lymphoma affecting the spleen, but the precise histological subtype (e.g., diffuse large B-cell, follicular, mantle cell) is unknown or not specified. This is often applicable in initial diagnostic stages or when pathology reports are inconclusive regarding the specific NHL type.

• Ensure the documentation explicitly states "spleen involvement" and "non-Hodgkin lymphoma."
• Avoid using this code if a more specific type of NHL is documented; always code to the highest level of specificity.
• Consider sequencing this code after a primary malignancy if the splenic involvement is metastatic, though NHL often presents as a systemic disease.