Other specified types of non-Hodgkin lymphoma, spleen

This diagnosis code signifies a malignant proliferation of lymphocytes in the spleen that does not fit into more specific categories of non-Hodgkin lymphoma. It represents a primary or secondary involvement of the spleen by a non-Hodgkin lymphoma type that is clearly identified but lacks a more precise ICD-10-CM code.

Apply this code when documentation specifies a non-Hodgkin lymphoma affecting the spleen, and the pathologist or clinician has identified a specific type (e.g., splenic marginal zone lymphoma, hairy cell leukemia variant) that does not have its own unique C-code. This code is appropriate when the spleen is the primary site of involvement or is clearly documented as an involved site in a disseminated disease.

• Ensure the medical record explicitly states splenic involvement and a specific, but uncoded, type of non-Hodgkin lymphoma.
• Differentiate from unspecified non-Hodgkin lymphoma of the spleen (C85.97) when a specific type is known.
• Always sequence this code according to the primary diagnosis guidelines, often as the principal diagnosis if the splenic lymphoma is the reason for the encounter.