Mediastinal (thymic) large B-cell lymphoma, nodes mult site

This code identifies a specific type of aggressive non-Hodgkin lymphoma originating from B-lymphocytes, primarily affecting the mediastinum (the area between the lungs). It is characterized by large B-cells and often presents as a bulky mass in the chest. The "lymph nodes of multiple sites" indicates the disease has spread beyond a single nodal region.

Use this code for patients diagnosed with mediastinal (thymic) large B-cell lymphoma where imaging or biopsy confirms involvement of lymph nodes in more than one anatomical region. Documentation must clearly specify both the histological subtype (large B-cell lymphoma) and the primary mediastinal origin, along with evidence of multifocal nodal involvement.

• Ensure documentation explicitly states "mediastinal" or "thymic" large B-cell lymphoma and "multiple sites" of lymph node involvement.
• Do not confuse with other types of large B-cell lymphoma (e.g., diffuse large B-cell lymphoma, not otherwise specified) or other mediastinal tumors.
• Always review pathology reports for definitive diagnosis and extent of disease.