Mediastinal (thymic) large B-cell lymphoma, spleen

This code signifies a diagnosis of mediastinal large B-cell lymphoma, a rare and aggressive subtype of non-Hodgkin lymphoma, specifically when the disease has metastasized to or originated in the spleen. This lymphoma typically arises in the mediastinum but can disseminate to other organs.

Apply this code when documentation explicitly states mediastinal large B-cell lymphoma with splenic involvement. This includes primary splenic involvement or metastatic disease to the spleen. Pathological confirmation of the lymphoma subtype and imaging/biopsy evidence of splenic involvement are necessary.

• Ensure the documentation clearly specifies "mediastinal" large B-cell lymphoma, not just general large B-cell lymphoma.
• Verify splenic involvement is documented, as this distinguishes it from other sites of metastasis.
• Sequence this code as the primary diagnosis when it is the reason for the encounter, or as a secondary diagnosis if another condition is being primarily treated.