Diffuse follicle center lymphoma, intrathoracic lymph nodes

This diagnosis code signifies a specific type of non-Hodgkin lymphoma characterized by a diffuse growth pattern of follicle center cells, located within the lymph nodes of the chest cavity. It represents a malignant proliferation of B-lymphocytes originating from germinal centers.

Use this code when diagnostic pathology confirms diffuse follicle center lymphoma and imaging or biopsy definitively identifies its presence in intrathoracic lymph nodes (e.g., mediastinal, hilar, or paratracheal lymph nodes). Documentation should clearly state both the histological subtype and the specific anatomical location.

• Ensure the pathology report explicitly states "diffuse" follicle center lymphoma, as other patterns exist.
• Verify the anatomical site is specifically "intrathoracic lymph nodes" to differentiate from extranodal or other nodal involvement.
• Do not confuse with follicular lymphoma, which has a different growth pattern and code.