Gammaherpesviral mononucleosis with other complications

This code signifies infectious mononucleosis caused by a gammaherpesvirus, such as Epstein-Barr virus (EBV), when the patient presents with complications beyond the typical symptoms of fever, fatigue, and lymphadenopathy. These complications can include hepatitis, splenic rupture, neurological involvement, or severe hematologic abnormalities.

Utilize this code when documentation clearly indicates a diagnosis of gammaherpesviral mononucleosis alongside specific, documented complications. This typically requires physician notes detailing the mononucleosis and the nature of the associated complication, such as "EBV mononucleosis with acute hepatitis" or "infectious mononucleosis with splenic rupture."

• Ensure the documentation explicitly states "gammaherpesviral" or identifies a specific gammaherpesvirus (e.g., EBV) as the causative agent.
• Do not use this code for uncomplicated gammaherpesviral mononucleosis; refer to B27.00.
• Code the specific complication(s) separately in addition to this code, following ICD-10-CM sequencing guidelines.