Chronic viral hepatitis B with delta-agent

This code signifies a persistent infection of the liver caused by the hepatitis B virus, complicated by co-infection with the hepatitis D (delta) virus. The delta agent can only replicate in the presence of HBV, and its presence often leads to more severe liver disease progression.

Use this code when documentation confirms chronic hepatitis B infection with evidence of active delta agent co-infection. This typically involves positive serological markers for both chronic HBV (e.g., HBsAg positive for >6 months) and HDV (e.g., anti-HDV or HDV RNA).

• Ensure documentation explicitly states "chronic" hepatitis B and "delta-agent" co-infection.
• Do not use for acute hepatitis B or acute delta co-infection; separate codes exist for those conditions.
• Consider sequencing this code before any associated complications of liver disease, such as cirrhosis or hepatocellular carcinoma, if present.