Esketamine antidepressant nasal spray, billed per 1 mg administered

This code represents a 1 mg unit of esketamine, a novel antidepressant administered intranasally. It is specifically formulated for the treatment of treatment-resistant depression (TRD) and major depressive disorder (MDD) with acute suicidal ideation or behavior. Esketamine acts as an N-methyl-D-aspartate (NMDA) receptor antagonist, offering a rapid onset of action for severe depressive symptoms.

Use this code when billing for the esketamine nasal spray administered in a supervised healthcare setting. This typically occurs in conjunction with an oral antidepressant for patients diagnosed with TRD or MDD with acute suicidality. Documentation should clearly indicate the drug's administration, dosage, and the patient's qualifying diagnosis.

• This code represents 1 mg of esketamine; ensure the billed units accurately reflect the total dosage administered (e.g., 56 mg would be 56 units).