Poisoning by anti-infectives and other drugs and preparations for ear, nose, and throat

This code signifies an adverse reaction or overdose resulting from anti-infective medications or other pharmaceutical preparations specifically intended for otic, nasal, or pharyngeal use. It indicates a toxic effect from these substances, rather than an allergic reaction or therapeutic failure.

Apply this code when documentation clearly states poisoning, overdose, or toxic effect due to drugs like topical antibiotics, decongestants, or anesthetics administered to the ear, nose, or throat. This includes accidental ingestion, incorrect dosage, or adverse systemic effects from local application.

• Always code the specific substance responsible for the poisoning using an E-code (E850-E869) in addition to this code.
• Distinguish between poisoning (toxic effect) and adverse effect (properly administered drug causing an untoward reaction), which would typically be coded with an E-code from E930-E949 and a manifestation code.
• Ensure documentation specifies the intent (accidental, intentional self-harm, undetermined) for the E-code.