False positive serological test for syphilis

This code indicates a laboratory finding where a serological test for syphilis, such as a VDRL or RPR, returns a positive result despite the absence of an active syphilis infection. This can occur due to various non-syphilitic conditions or factors that cause cross-reactivity with the test reagents.

Use this code when documentation clearly states a positive serological test for syphilis, but subsequent confirmatory tests (e.g., FTA-ABS, TP-PA) are negative, or clinical evidence rules out active syphilis. This code is appropriate when the patient is being evaluated for the cause of the false positive.

• Always confirm with confirmatory test results or clinical assessment before assigning this code.
• Do not use this code if the patient has active syphilis; instead, code the specific stage of syphilis.
• Consider coding any underlying conditions causing the false positive, such as autoimmune diseases, viral infections, or pregnancy, as additional diagnoses.