Pernicious anemia

This code signifies pernicious anemia, a megaloblastic anemia caused by malabsorption of vitamin B12 due to a lack of intrinsic factor. This autoimmune condition leads to impaired red blood cell production and can result in neurological complications if left untreated.

Use this code when documentation explicitly states a diagnosis of pernicious anemia, often confirmed by intrinsic factor antibody tests, Schilling test results, or characteristic peripheral blood smear findings (macrocytic, normochromic anemia). It is appropriate for both initial diagnosis and ongoing management of the condition.

• Ensure documentation clearly distinguishes pernicious anemia from other B12 deficiency anemias not caused by intrinsic factor deficiency.
• Always sequence this code as the primary diagnosis when it is the reason for the encounter.
• Look for associated neurological manifestations (e.g., peripheral neuropathy) which may require additional coding.