Panhypopituitarism

This code represents a rare endocrine disorder characterized by the complete or near-complete deficiency of all anterior pituitary hormones. This deficiency leads to a wide range of systemic symptoms due to the lack of essential hormones like TSH, ACTH, GH, LH, and FSH.

Use this code when documentation clearly indicates a global failure of the anterior pituitary gland, resulting in multiple hormone deficiencies. This diagnosis is typically supported by laboratory findings showing low levels of multiple pituitary hormones and their target gland hormones, often in conjunction with imaging studies revealing pituitary pathology.

• Ensure documentation specifies "panhypopituitarism" rather than partial pituitary deficiencies.
• Code any underlying cause of the panhypopituitarism (e.g., pituitary tumor, Sheehan's syndrome) as a primary diagnosis if known and clinically relevant.
• Do not confuse with isolated pituitary hormone deficiencies, which have separate codes.