Cryptococcosis

This code represents cryptococcosis, a systemic fungal infection caused by Cryptococcus neoformans or Cryptococcus gattii. It primarily affects the lungs but can disseminate to the central nervous system, causing meningitis, and less commonly to other organs like the skin, bones, or prostate.

Use this code for confirmed cases of cryptococcal infection, regardless of the primary site of involvement. Documentation should clearly state the diagnosis of cryptococcosis, often supported by laboratory findings such as positive fungal cultures, antigen detection (e.g., cryptococcal antigen test), or histopathological examination.

• Specify the manifestation if possible (e.g., cryptococcal meningitis, cryptococcal pneumonia) using additional codes.
• Always code any associated immunocompromised state (e.g., HIV infection, organ transplant, corticosteroid use) as a secondary diagnosis.
• Distinguish from other systemic mycoses; this code is specific to Cryptococcus species.