Personal history of monoclonal drug therapy

This code indicates a patient's past medical history of having received treatment with monoclonal antibodies. These are laboratory-produced molecules engineered to mimic the body's natural antibodies, often used to target specific cells or proteins in various diseases, including cancers and autoimmune disorders. The therapy itself is no longer active, but the history is relevant for ongoing care.

Assign this code when a patient has completed a course of monoclonal drug therapy in the past, and this history is pertinent to their current medical management. This is commonly seen in follow-up care for oncology patients who received such treatments, or for individuals with chronic autoimmune conditions previously managed with monoclonal antibodies. It signifies a completed treatment, not an active one.

• Do not use this code for current or active monoclonal drug therapy; instead, code the specific encounter for the administration of the drug.
• Distinguish this from a personal history of immune checkpoint inhibitor therapy (Z92.26), which is a specific type of monoclonal antibody.
• Always sequence this code as a secondary diagnosis, as it represents a historical condition influencing current care, not the primary reason for the encounter.