Acquired absence of spleen

This code signifies the permanent removal or non-existence of the spleen due to a medical intervention or disease process, rather than a congenital condition. Patients with an acquired absence of the spleen are at increased risk for certain infections and may require lifelong prophylactic measures.

Apply this code when documenting a patient's history of splenectomy, whether performed due to trauma, hematological disorders (e.g., idiopathic thrombocytopenic purpura, hereditary spherocytosis), or other medical necessity. It is also appropriate for cases where the spleen has atrophied or been destroyed by disease.

• Always confirm the absence is acquired, not congenital (Q89.01 for congenital absence).
• Code this as a secondary diagnosis when the patient is being seen for a condition related to or complicated by asplenia.
• Do not use this code for a patient who still has their spleen, even if it is dysfunctional or enlarged.